pentobarbital will reduce the extent or outcome of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Mysterious.pentobarbital will reduce the level or effect of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Powerful CYP3A4 inducers might decrease midostaurin co